Trends In Medicinal Chemistry Research Articles

Recent trends in medicinal chemistry and enabling technologies. Highlights from the Society for Medicines Research Conference. London - December 8, 2022

Recent trends in medicinal chemistry and enabling technologies. Highlights from the Society for Medicines Research Conference. London - December 8, 2022

EFMC: Trends in Medicinal Chemistry and Chemical Biology.

Ground-breaking research in disease biology and continuous efforts in method development have uncovered a range of potential new drug targets. Increasingly, the drug discovery process is informed by technologies involving chemical probes as tools. Applications for chemical probes comprise target identification and assessment, as well as the qualification of small molecules as chemical starting points and drug candidates. Progress in probe chemistry has opened the way to novel assay formats and pharmaceutical compound classes. The European Federation of Medicinal Chemistry and Chemical Biology (EFMC) has launched the Chemical Biology Initiative to advance science in the field of medicinal chemistry and chemical biology, while representing all members of this extended scientific community. This review provides an overview of the many important developments in the field of chemical biology that have happened at the lively interface of academic and industrial research.

Trends in medicinal chemistry. Highlights from the society for medicines research symposium. London, UK - December 6, 2018

Trends in medicinal chemistry. Highlights from the society for medicines research symposium. London, UK - December 6, 2018

Trends in medicinal chemistry: Highlights from the Society for Medicines Research Symposium, held December 3, 2015 - National Hearth and Lung Institute, London, UK

Trends in medicinal chemistry: Highlights from the Society for Medicines Research Symposium, held December 3, 2015 - National Hearth and Lung Institute, London, UK

Short Commentary on Current Trends in Medicinal Chemistry of the Central Nervous System

As a result, medicinal chemistry, which has emerged from organic chemistry, has undergone multiple trends and – depending on the indications – with various results. Many diseases have been eradicated, resulting in better quality of life and its elongation (e.g. analgesic, nontropic drugs). Other indications have arose and became unmet medical needs (e.g. neuropathic pain). Moreover, there are diseases which were poorly addressed fifty years ago and are still today (e.g. epilepsy, major depressive disorder).

Current Trends in Medicinal Chemistry

Current Trends in Medicinal Chemistry

Interview with Graham Warrellow

Following his academic studies at the University of Surrey (UK), Graham Warrellow entered the pharmaceutical industry to pursue a career at the forefront of drug discovery. Following successful spells at Wyeth, Celltech and Almirall, he joined UCB as the Vice President for Chemistry UK. Through this role and as a director at Cyclofluidic, a joint venture of UCB and Pfizer, he has witnessed changing trends in medicinal chemistry R&D over recent years. Dr Warrellow speaks to Isaac Bruce, Commissioning Editor, about industry collaborations, what qualities make for a good medicinal chemist and the future of the pharmaceutical industry.

Conference Report: Bridging Gaps in Discovery and Development: Chemical and Biological Sciences for Affordable Health, Wellness and Sustainability

To commemorate 2011 as the International Year of Chemistry, the Indian Society of Chemists and Biologists organized its 15th International Conference on 'Bridging Gaps in Discovery and Development: Chemical and Biological Sciences for Affordable Health, Wellness and Sustainability' at Hotel Grand Bhagwati, in association with Saurashtra University, Rajkot, India. Anamik Shah, President of the Indian Society of Chemists and Biologists, was organizing secretary of the conference. Nicole Moreau, President of the International Union of Pure and Applied Chemistry and Secretary General of the Comité National de la Chimie, National Centre for Scientific Research France, was chief guest of the function. The four-day scientific program included 52 plenary lectures, 24 invited lectures by eminent scientists in the field and 12 oral presentations. A total of 317 posters were presented by young scientists and PhD students in three different poster sessions. Approximately 750 delegates from India, the USA, UK, France, Switzerland, Germany, Austria, Belgium, Sweden, Japan and other countries attended the conference. The majority of the speakers gave presentations related to their current projects and areas of interest and many of the talks covered synthesis, structure-activity relationships, current trends in medicinal chemistry and drug research.

Trends in medicinal chemistry: Highlights from the Society for Medicines Research Symposium held on December 9, 2010 at NHLI, London, UK

On December 9, 2010, the Society for Medicines Research held a one-day meeting entitled Trends in Medicinal Chemistry. This symposium, organized by Phillip Cowley, Neil Hales and Simon Ward, brought together a panel of international speakers to present and discuss the advances that are currently being made. In recent years, there have been significant changes to the landscape of the pharmaceutical industry. The aim of this meeting was to allow scientists within drug discovery programs in biotech, pharma and academia to be updated on new methodologies and screening approaches, as well as capture best practices from key case study presentations.

Trends in medicinal chemistry: Highlights from the Society for Medicines Research Symposium held on December 9, 2010 at NHLI, London, UK

Trends in medicinal chemistry: Highlights from the Society for Medicines Research Symposium held on December 9, 2010 at NHLI, London, UK

Conference Report: 4th Anglo–Swedish Medicinal Chemistry Symposium

The Anglo-Swedish Medicinal Chemistry Symposium is normally held in the skiing resort of Are in Sweden, but this year, for the first time, the meeting was held at the AstraZeneca R&D site in Lund. The meeting was divided into five sections, consisting of a total of 19 high-quality lectures. In chronological order these sections were: kinases and ATPases; overcoming problems associated with multifunctional targets; achieving selectivity by tissue distribution; enzymes and transporters; challenges and trends in medicinal chemistry; and G protein-coupled receptors.

New Trends in Medicinal Chemistry Approaches to Antiobesity Therapy

The prevalences of overweightedness and obesity are increasing globally at frightening rates, driven by social and economic changes. Furthermore, obesity is associated with the pathogeneses of major diseases, particularly diabetes and cardiovascular diseases. However, no satisfactorily safe, effective obesity drugs are commercially available at the present time. Only two drugs have been approved in the United States for the long-term treatment of obesity, sibutramine and orlistat. However, these drugs are minimally effective and have significant side effects, which are likely inhibit their use. Therefore, there is a huge opportunity to make a significant impact on the lives of obese people through the discovery and development of additional pharmacotherapeutic options. In this review article, the authors focus on selected trends in medicinal chemistry and the approaches used to develop drugs for treating obesity.